GMPR: A robust normalization method for zero-inflated count data with application to microbiome sequencing data
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چکیده
منابع مشابه
GMPR: A robust normalization method for zero-inflated count data with application to microbiome sequencing data
Normalization is the first critical step in microbiome sequencing data analysis used to account for variable library sizes. Current RNA-Seq based normalization methods that have been adapted for microbiome data fail to consider the unique characteristics of microbiome data, which contain a vast number of zeros due to the physical absence or under-sampling of the microbes. Normalization methods ...
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ژورنال
عنوان ژورنال: PeerJ
سال: 2018
ISSN: 2167-8359
DOI: 10.7717/peerj.4600